FB2026_02 , released June 18, 2026
Allele: Dmel\caly2
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General Information
Symbol
Dmel\caly2
Species
D. melanogaster
Name
FlyBase ID
FBal0218277
Feature type
allele
Associated gene
Dmel\caly
Associated Insertion(s)
Carried in Construct
Also Known As
calypso2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(de Ayala Alonso et al., 2007)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C?T.

(Scheuermann et al., 2010)

Amino acid replacement: Q41term.

(Scheuermann et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:16,195,789..16,195,789 [-]
Nucleotide change:

C16195789T

Reported nucleotide change:

C?T

Amino acid change:

Q41term | caly-PA; Q41term | caly-PB

Reported amino acid change:

Q41term

(Scheuermann et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos derived from homozygous female germ-line clones die at the end of embryogenesis with homeotic transformations that are characteristic of Polycomb group mutants; abdominal segments 5 to 7 are transformed into copies of the 8th abdominal segment.

      (de Ayala Alonso et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      calypso2 ScmD1/ScmSuz302 double mutant clones in the wing disc do not show a tumour-like phenotype.

      (Grimm et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      caly1

      (de Ayala Alonso et al., 2007)
      Rescued by

      Df(2R)Exel6063/caly2 is rescued by calyαTub84B.Tag:TAP

      (Scheuermann et al., 2010)
      Comments

      calypsoαTub84B.T:Zzzz\TAP fully rescues the viability and fertility of calypso2/Df(2R)Exel6063 animals.

      (Scheuermann et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (7)