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General Information
Symbol
Dmel\GSd312GSd312
Species
D. melanogaster
Name
FlyBase ID
FBal0218658
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GSd312
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GSV1}GSd312GSd312
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Expression of GSd312GSd312 under the control of Scer\GAL4109(2)80 results in defects in the dendrites of dorsal cluster dendritic arborisation (da) neurons in third instar larvae: dendrite morphology is defective in the class III da neurons and dendrite branching is reduced in the class IV da neurons.

    Isolated RP2 neuron clones expressing GSd312GSd312 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show a reduction in dendrite growth and a reduction in the number of dendritic branch points at 25-31 hours after egg laying. The distribution of dendrites in the dendritic field is altered: there is a decrease in the number of dendrites targeted to the anterior, posterior, medial and lateral regions of the dendritic field.

    Fas2-positive axon bundles in the ventral nerve cord are missing or disrupted in embryos expressing GSd312GSd312 under the control of Scer\GAL4scrt-11-6. In the periphery, the SNa motor neuron is missing or thinned, and the ISNb motor neuron is stalled or misrouted.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    GSd312GSd312
    Name Synonyms
    Secondary FlyBase IDs
      References (3)