Expression of GSd312GSd312 under the control of Scer\GAL4109(2)80 results in defects in the dendrites of dorsal cluster dendritic arborisation (da) neurons in third instar larvae: dendrite morphology is defective in the class III da neurons and dendrite branching is reduced in the class IV da neurons.
Isolated RP2 neuron clones expressing GSd312GSd312 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show a reduction in dendrite growth and a reduction in the number of dendritic branch points at 25-31 hours after egg laying. The distribution of dendrites in the dendritic field is altered: there is a decrease in the number of dendrites targeted to the anterior, posterior, medial and lateral regions of the dendritic field.
Fas2-positive axon bundles in the ventral nerve cord are missing or disrupted in embryos expressing GSd312GSd312 under the control of Scer\GAL4scrt-11-6. In the periphery, the SNa motor neuron is missing or thinned, and the ISNb motor neuron is stalled or misrouted.