FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Pi3K92E6M5
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General Information
Symbol
Dmel\Pi3K92E6M5
Species
D. melanogaster
Name
FlyBase ID
FBal0218870
Feature type
allele
Associated gene
Dmel\Pi3K92E
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Orme et al., 2006)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Pi3K92E6M5 generates a weakly interfering mutation in the kinase domain of the Pi3K92E protein.

    (Orme et al., 2006)

    Amino acid replacement: G823D.

    (Orme et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:20,630,792..20,630,792 [-]
    Nucleotide change:

    G20630792A

    Amino acid change:

    G823D | Pi3K92E-PA; G823D | Pi3K92E-PB; G823D | Pi3K92E-PC

    Reported amino acid change:

    G823D

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (Orme et al., 2006)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Pi3K92E6M5/Pi3K92E6V2 females lay no eggs at all and their ovaries cannot be located.

        (Orme et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Dp1106M5
        (Orme et al., 2006)
        Pi3K92E6M5
        Name Synonyms
        Secondary FlyBase IDs
          References (1)