FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DCP1442P
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General Information
Symbol
Dmel\DCP1442P
Species
D. melanogaster
Name
FlyBase ID
FBal0219707
Feature type
allele
Associated gene
Dmel\DCP1
Associated Insertion(s)
Carried in Construct
Also Known As
dDcp1442P
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    DCP1GS11684
    (Lin et al., 2006)
    Cytology
    Description

    Imprecise excision of the P{GSV6} element in Dcp1GS11684, resulting in a 274bp deletion, into which 28bp of unknown origin has been inserted. The deletion extends from -27 to +247bp relative to the translation start site of Dcp1.

    (Lin et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    delins
    2R:23,889,946..23,890,219 [-]
    Comment:

    A 274bp deletion resulting from the imprecise excision of P{GSV6}DCP1GS11684. A 28bp sequence of unknown origin has been inserted. The deletion is reported as extending from -27 to +247bp relative to the DCP1 translation start site.

    Inserted_sequence:

    NNNNNNNNNNNNNNNNNNNNNNNNNNNN

    (Lin et al., 2006)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The average size of P bodies (detected using pcm antibody) in nurse cell cytoplasm in ovaries from Dcp1442P; Dcp1tT2.R57A/+ females is increased ~2.6 times compared to that of controls.

        (Lin et al., 2008)

        Females containing homozygous germ-line clones produce egg chambers that arrest by stage 6.

        (Lin et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        DCP1442P is rescued by DCP1tT2

        (Lin et al., 2006)
        Comments

        P{Dcp1.T2} rescues the lethality of Dcp1442P homozygotes.

        (Lin et al., 2006)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        DCP1442P
        Dcp1442P
        (Lin et al., 2006)
        dDCP1442P
        (Hakes and Gavis, 2023)
        dDcp1442P
        (Lin et al., 2008)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)