FlyBase Allele Report: Dmel\XNP[1]

General Information

Symbol

Dmel\XNP¹

Species

D. melanogaster

Name

FlyBase ID

FBal0220138

Feature type

allele

Associated gene

Dmel\XNP

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Bassett et al., 2008)

Mutagen

Delta2-3 transposase

(Bassett et al., 2008)

Progenitor genotype

P{EP}XNP^EP635

(Bassett et al., 2008)

Caused by aberration

Df(3R)XNP¹

Cytology

Description

Imprecise excision of the P{EP}XNP^EP635 insertion, resulting in a 7.5kb deletion that includes the entire XNP open reading frame, the neighbouring MED28 and CG4553 genes, and some of the 3' untranslated region of CG5127.

(Bassett et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with XNP²)

(López-Falcón et al., 2014)

partially lethal - majority die (with XNP³)

(López-Falcón et al., 2014)

suppressor of variegation | dominant, with In(1)w^m4h

(Bassett et al., 2008)

suppressor of variegation | dominant, with P{hsp26-pt-T}39C-12

(Bassett et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

XNP¹/XNP² or XNP¹/XNP³ flies have reduced viability and no melanotic masses (XNP¹/+, XNP²/+ or XNP³/+ flies are viable and have no melanotic masses).

(López-Falcón et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

ADD1^NP0793, XNP¹/XNP[+] has melanotic mass phenotype | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP[+] has melanotic mass phenotype | larval stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP[+] has melanotic mass phenotype | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP³ has melanotic mass phenotype | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP²/XNP¹ has melanotic mass phenotype | larval stage phenotype

(López-Falcón et al., 2014)

Phenotype Manifest In

Other

Statement

Reference

ADD1^NP0793, XNP¹/XNP[+] has melanotic mass | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP[+] has melanotic mass | larval stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP[+] has melanotic mass | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP¹/XNP³ has melanotic mass | adult stage phenotype

(López-Falcón et al., 2014)

ADD1^NP1240, XNP²/XNP¹ has melanotic mass | larval stage phenotype

(López-Falcón et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

26642

w^*; Df(3R)XNP¹, XNP¹/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

XNP¹

atrx¹

(López-Falcón et al., 2014)

dATRX¹

(Bassett et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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