FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nup160e00704
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General Information
Symbol
Dmel\Nup160e00704
Species
D. melanogaster
Name
FlyBase ID
FBal0220491
Feature type
allele
Associated gene
Dmel\Nup160
Associated Insertion(s)
PBac{RB}RfC38e00704
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    PBac{RB}RfC38e00704
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    PBac{RB}
    Also carries
    FRT
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Nup160e00704 homozygotes are inviable.

        (Sawamura et al., 2010)

        Nup160e00704 causes hybrid lethality in Dmel X Dsim males carrying a Dmel X chromosome and in Dmel X Dsim females carrying 2 Dmel X chromosomes (as the attached X C(1)A)Q1 This lethality is not seen in males or females of the same genotype apart from carrying a Dsim X, or in the progeny of wild-type Dmel X Dsim crosses.

        (Tang and Presgraves, 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Nup160e00704 is rescued by Nup160UAS.cTa/Scer\GAL4Tub.PU

        (Tang and Presgraves, 2009)
        Comments

        Dmel X Dsim hybrid male lethality due to Nup160e00704 is rescued by Nup160Scer\UAS.cTa.

        (Tang and Presgraves, 2009)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of PBac{RB}RfC38e00704 reverts the hybrid male lethality of Nup160e00704/Dsim[+].

        (Tang and Presgraves, 2009)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Nup160e00704
        (Maehara et al., 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)