FB2026_02 , released June 18, 2026
Allele: Dmel\Vsx1A23
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General Information
Symbol
Dmel\Vsx1A23
Species
D. melanogaster
Name
FlyBase ID
FBal0220517
Feature type
allele
Associated gene
Dmel\Vsx1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Erclik et al., 2008)
Mutagen
Delta2-3 transposase
(Erclik et al., 2008)
Progenitor genotype
Vsx1P28
(Erclik et al., 2008, Erclik et al., 2008)
Cytology
Description

Imprecise excision of the insertion in Vsx1P28, resulting in a deletion of 4kb proximal to the site of the original insertion.

(Erclik et al., 2008)

Imprecise excision of the insertion in Vsx1P28, resulting in a deletion and inversion of Vsx1 sequences, which removes the nuclear localisation signal of Vsx1.

(Erclik et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants show lethality at all postembryonic stages. Mutants show developmental defects, with the time taken to reach the molt to second instar from hatching being increased relative to controls.

      Mutant pharate adults have significantly smaller optic lobes than control animals.

      (Erclik et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      A23
      (Erclik et al., 2008)
      Chx1A23
      (Hwang and Rulifson, 2011)
      Vsx1A23
      dVsxA23
      (Erclik et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)