FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\appRNAi.UAS.cMa
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General Information
Symbol
Dmel\appRNAi.UAS.cMa
Species
D. melanogaster
Name
FlyBase ID
FBal0220522
Feature type
allele
Associated gene
Dmel\app
Associated Insertion(s)
Carried in Construct
P{UAS-app.RNAi.M}
Also Known As
UAS-app-RNAi
Key Links
Transgenic product class
RNAi_reagent
(Matakatsu and Blair, 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Matakatsu and Blair, 2008)
Mutagen
in vitro construct
(Matakatsu and Blair, 2008)
Progenitor genotype
Carried in construct
P{UAS-app.RNAi.M}
Cytology
Description

UAS regulatory sequences drive expression of an RNAi transgene corresponding to the 5' end of app.

(Matakatsu and Blair, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
app
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing appdsRNA.Scer\UAS.cMa under the control of Scer\GAL4ap-md544 have planar cell polarity defects on the dorsal wing surface and the distance between the anterior crossvein and the posterior crossvein is reduced compared to controls.

      (Matakatsu and Blair, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of appdsRNA.Scer\UAS.cMa under the control of Scer\GAL4Act.PU fails to suppress the head overgrowth seen in mopsfv3 Df(3L)H99 mutant clones (generated in a minute background).

      (Gilbert et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      appRNAi.UAS.cMa
      appdsRNA.Scer\UAS.cMa
      appdsRNA.UAS.cMa
      Name Synonyms
      Secondary FlyBase IDs
        References (5)