FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\alcUAS.cSa
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General Information
Symbol
Dmel\alcUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Spasic
FlyBase ID
FBal0221006
Feature type
allele
Associated gene
Dmel\alc
Associated Insertion(s)
Carried in Construct
P{UAS-alc.S}
Also Known As
UAS-alc
Key Links
Transgenic product class
cDNA
(Spasić et al., 2008)
wild_type
(Spasić et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Spasić et al., 2008)
wild_type
(Spasić et al., 2008)
Mutagen
in vitro construct
(Spasić et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-alc.S}
Cytology
Description

UASt sequences govern expression of alc-RA cDNA RE12077 in which single nucleotide changes compared to genomic sequence (T95A and V133A) have been reverted.

(Spasić et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
alc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      alcUAS.cSa/Scer\GAL4ey.PH rescues alcΔ12.125

      (Spasić et al., 2008)

      alcUAS.cSa/Scer\GAL4da.G32 rescues Df(2R)Np5/alcΔ12.125

      (Spasić et al., 2008)

      alcUAS.cSa/Scer\GAL4Tub.PU rescues Df(2R)Np5/alcΔ12.125

      (Spasić et al., 2008)

      alcUAS.cSa/Scer\GAL4da.G32 rescues alcAd2

      (Spasić et al., 2008)

      alcUAS.cSa/Scer\GAL4Tub.PU rescues alcAd2

      (Spasić et al., 2008)
      Comments

      Behavioral phenotypes, neuro-degeneration and aberrant ERG profiles seen in adults with alcΔ12.125 homozygous eyes and antennae (inducing homozygous somatic clones in the eye and antenna with Scer\GAL4ey.PH; Scer\FLP1Scer\UAS.cDa and killing non-mutant cells in the eye with WGMR.PG) are rescued by alcScer\UAS.cSa; Scer\GAL4ey.PH.

      (Spasić et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      alcScer\UAS.cSa
      alcUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Spasic
      Secondary FlyBase IDs
        References (3)