FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dpy-30L1UAS.cVa
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General Information
Symbol
Dmel\Dpy-30L1UAS.cVa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Vardanyan
FlyBase ID
FBal0221321
Feature type
allele
Associated gene
Dmel\Dpy-30L1
Associated Insertion(s)
Carried in Construct
P{UAS-Dpy-30L1.V}
Key Links
Transgenic product class
wild_type
(Vardanyan et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Vardanyan et al., 2008)
Mutagen
in vitro construct
(Vardanyan et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Dpy-30L1.V}
Cytology
Description

UAS regulatory sequences drive expression of Dpy-30L1.

(Vardanyan et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dpy-30L1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Dpy-30L1Scer\UAS.cVa under the control of Scer\GAL4Act are more sensitive to cadmium or zinc in the food medium compared to controls, while sensitivity to copper is only marginally affected.

      Flies expressing Dpy-30L1Scer\UAS.cVa under the control of Scer\GAL4Act show the same sensitivity to excess iron in the food medium as wild-type controls.

      (Vardanyan et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Dpy-30L1UAS.cVa, Scer\GAL4Act.PU has chemical sensitive phenotype, suppressible by MTF-1Tub.PY

      (Vardanyan et al., 2008)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased sensitivity of flies expressing Dpy-30L1Scer\UAS.cVa under the control of Scer\GAL4Act to cadmium or zinc in the food medium is rescued by co-expression of MTF-1Tub.PY.

      (Vardanyan et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dpy-30L1Scer\UAS.cVa
      Dpy-30L1UAS.cVa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Vardanyan
      Secondary FlyBase IDs
        References (1)