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General Information
Symbol
Hsap\LAMP1UAS.EGFP
Species
H. sapiens
Name
FlyBase ID
FBal0221465
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Lamp1-GFP, LAMP1-GFP, UAS-GFP-Lamp1, GFP-LAMP1, LAMP-GFP, GFP-LAMP, UAS-GFP-LAMP, UAS GFP-Lamp1, UAS-GFP:Lamp1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a cleavable preprolactin signal sequence, followed by EGFP and then the transmembrane domain and cytoplasmic tail of Hsap\LAMP1 (the cytoplasmic tail is sufficient to direct the protein produced to late endosomes and lysosomes).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhancer of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Scer\GAL4hh-Gal4-mediated expression of Hsap\LAMP1Scer\UAS.T:Avic\GFP-EGFP has no effect on the ectopic N activation phenotype (ectopic expression of wg) in the posterior of l(2)gd1d7 wing discs.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Hsap\LAMP1Scer\UAS.T:Avic\GFP-EGFP
Hsap\LAMP1UAS.EGFP
Name Synonyms
Secondary FlyBase IDs
    References (50)