FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\APP-BP1Ex183
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General Information
Symbol
Dmel\APP-BP1Ex183
Species
D. melanogaster
Name
FlyBase ID
FBal0221555
Feature type
allele
Associated gene
Dmel\APP-BP1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kim et al., 2007)
Progenitor genotype
P{lacZ}APP-BP1LP67
(Kim et al., 2007)
Cytology
Description

The deleted region in APP-BP1Ex183 is from 11090085 to 11091705 (1621bp).

(Kim, 2012.1.10)

Imprecise excision of the progenitor insertion, resulting in a deletion of 1621bp, including 84bp of the APP-BP1 5'UTR.

(Kim et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:11,096,985..11,098,631 [+]
Comment:

A 1621 bp deletion resulting from the imprecise excision of P{lacZ}APP-BP1LP67.

(Kim, 2012.1.10, Kim et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous clones are recovered in adult eyes, but the homozygous clones are substantially smaller than wild-type clones.

      Homozygous clones in the wing disc are similar in size to their wild-type twin spots.

      (Kim et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      APP-BP1[+]/APP-BP1Ex183 is a non-suppressor of visible phenotype of Appld

      (Kim et al., 2007)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      APP-BP1[+]/APP-BP1Ex183 is a non-suppressor of anterior scutellar bristle phenotype of Appld

      (Kim et al., 2007)

      APP-BP1[+]/APP-BP1Ex183 is a non-suppressor of posterior scutellar bristle phenotype of Appld

      (Kim et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The loss of anterior and posterior scutellar macrochaetae that is seen in Appld flies is not suppressed by APP-BP1Ex183/+.

      (Kim et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      APP-BP1Ex183
      dAPP-BP1Ex183
      (Kim, 2012.1.10)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)