FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mrn9
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General Information
Symbol
Dmel\mrn9
Species
D. melanogaster
Name
FlyBase ID
FBal0221609
Feature type
allele
Associated gene
Dmel\mrn
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Matsuno et al., 2007)
Progenitor genotype
mrnEP572
(Matsuno et al., 2007)
Cytology
Description

Imprecise excision of the insertion in mrnEP572, resulting in 989bp of genomic DNA (+6 to +994 relative to the first nucleotide of the translation initiation codon) being deleted and replaced with 24bp of unrelated sequence.

(Matsuno et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
sequence_alteration
3L:15,579,513..15,580,501 [-]
Comment:

Deletion of 989bp and insertion of 24 bases of unrelated sequence as a result of imprecise excision of P{EP}mrnEP572

(Matsuno et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mutant clones induced in the eye using the eyFLP method are hardly detected in the adult eye. Homozygous mutant clones induced in the eye using the eyFLP method in a Minute/+ background are recovered in the eye disc, although these clones are much smaller than control clones.

      Massive apoptosis is induced in homozygous clones in the eye disc 4 hours after UV irradiation of 500 J/m[2] (apoptosis is not induced in wild-type clones under these conditions).

      BrdU incorporation is reduced in the central nervous system and eye imaginal disc of homozygous first instar larvae compared to wild-type controls.

      (Matsuno et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      mrn9 is rescued by mrnUAS.cMa/Scer\GAL4ey.PH

      (Matsuno et al., 2007)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ex9-2
      (Matsuno et al., 2007)
      mrn9
      (Matsuno et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)