FB2026_02 , released June 18, 2026
Allele: Dmel\PsaGMR.Ex.PK
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General Information
Symbol
Dmel\PsaGMR.Ex.PK
Species
D. melanogaster
Name
FlyBase ID
FBal0221642
Feature type
allele
Associated gene
Dmel\Psa
Associated Insertion(s)
Carried in Construct
P{GMR-Psa.Ex}
Key Links
Transgenic product class
wild_type
(Karsten et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Karsten et al., 2006)
Mutagen
in vitro construct
(Karsten et al., 2006)
Progenitor genotype
Carried in construct
P{GMR-Psa.Ex}
Cytology
Description

GMR regulatory sequences drive expression of Psa.

(Karsten et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
Psa
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  tauopathy
      modeled by Hsap\MAPTGMR.Ex.PJ
      (Karsten et al., 2006)
      modeled by Hsap\MAPTP301L.GMR
      (Karsten et al., 2006)
      ameliorates  Huntington's disease
      modeled by Hsap\HTTGMR.Q120
      (Menzies et al., 2010)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying PsaGMR.Ex.PK have a normal eye.

      (Karsten et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      PsaGMR.Ex.PK is a suppressor of abnormal neuroanatomy | progressive phenotype of Hsap\HTTGMR.Q120

      (Menzies et al., 2010)

      PsaGMR.Ex.PK is a suppressor of visible phenotype of Hsap\MAPTP301L.GMR

      (Karsten et al., 2006)

      PsaGMR.Ex.PK is a suppressor of visible phenotype of Hsap\MAPTGMR.Ex.PJ

      (Karsten et al., 2006)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      PsaGMR.Ex.PK is a suppressor of rhabdomere of eye photoreceptor cell phenotype of Hsap\HTTGMR.Q120

      (Menzies et al., 2010)

      PsaGMR.Ex.PK is a suppressor of eye phenotype of Hsap\MAPTP301L.GMR

      (Karsten et al., 2006)

      PsaGMR.Ex.PK is a suppressor of eye phenotype of Hsap\MAPTGMR.Ex.PJ

      (Karsten et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Overexpression of PsaGMR.Ex.PK in flies also expressing Hsap\HTTGMR.Q120 increases the number of visible photoreceptors.

      (Menzies et al., 2010)

      The rough eye phenotype caused by Hsap\MAPTGMR.Ex.PJ is suppressed by co-expression of PsaGMR.Ex.PK.

      The rough eye phenotype caused by Hsap\MAPTP301L.GMR is suppressed by co-expression of PsaGMR.Ex.PK.

      (Karsten et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      PsaGMR.Ex.PK
      Name Synonyms
      Secondary FlyBase IDs
        References (2)