32.62% of homozygous larvae die at 19[o]C. 60.88% of homozygotes eclose as adults at this temperature. These flies have scalloped wings. The scalloped phenotype is variable, ranging from middle scalloping in the posterior to strong scalloping in the anterior and posterior compartments. The strong phenotype is more frequent in females than in males.
40.75% of homozygous larvae and 14.23% of homozygous pupae die at 25[o]C. 49.10% of the animals eclose as adults at this temperature.
52.57% of homozygous larvae and 100% of homozygous pupae die at 29[o]C. None of the homozygotes eclose as adults at this temperature. Animals that are helped to emerge are sometimes unable to move the lower abdomen, usually have deformed tarsal segments of the T3 leg and die in less than 3 hours.
Homozygous flies raised to adulthood at 19[o]C and then incubated at 29[o]C show a dramatic reduction in lifespan compared to control flies. The death rate is higher in mutant males than in mutant females from the second to the sixth day.
wiserts1/Df(1)RA2 results in lethality at both 19[o]C and 29[o]C. wiserts1/Df(1)RA2 adult escapers have a strong scalloped wing phenotype in the anterior and posterior compartments, smaller and rougher eyes than normal, deformed T3 legs, locomotor defects, are sterile with deformed ovaries and die after 1-4 days.
Excision of the P-element insertion reverts the mutant phenotype.