FlyBase Aberration Report: Dmel\Df(1)RA2

General Information

Symbol

Df(1)RA2

Species

D. melanogaster

Name

FlyBase ID

FBab0000663

Feature type

chromosomal_deletion

Computed Breakpoints include

7D18-7D22;8A4

Features within 7D18--8A4

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Porsch et al., 1998, Min and Benzer, 1997, Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Dorer et al., 1993, Silva et al., 1991, Ayyub et al., 1990, Prudhommeau and Proust, 1990, Bieber et al., 1989, King et al., 1986, Lineruth et al., 1985, Deak et al., 1982, Craymer and Roy, 1980)

Breakpoints

7D10;8A4-8A5

(Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Anand and Chandra, 1994, Silva et al., 1991, Ayyub et al., 1990, Bieber et al., 1989, King et al., 1986, Lineruth et al., 1985, Deak et al., 1982, Craymer and Roy, 1980)

7D10;8A4

(Min and Benzer, 1997)

7D8;8A5

(Prudhommeau and Proust, 1990)

7D18-7D22;8A4-8A5

(Porsch et al., 1998, Dorer et al., 1993)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(1)ESHS36 << bk1 << eggroll << l(1)7Do << bk2 << rdgA

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Stewart and Denell, 1993)

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0058587) Right limit of break 1 from inclusion of l(1)7Dm (FBrf0105246) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0099402)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

eggroll

(Min and Benzer, 1997)

fs(1)h

(Schalet, 1986)

(Craymer and Roy, 1980)

(Dorer et al., 1993)

l(1)7Dg

(Zheng et al., 2003)

l(1)7Dh

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Di

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Dj

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Dk

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Dl

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Dm

(Henderson and Andrew, 1998)

l(1)7Do

(Eeken et al., 1985)

l(1)7Fg

(Eeken et al., 1985)

l(1)A36.3

(Proust et al., 1992)

l(1)ESHS32

(Eeken et al., 1985)

l(1)ESHS38

(Eeken et al., 1985)

l(1)ESHS39

(Eeken et al., 1985)

l(1)L60.6

(Proust et al., 1992)

lawc

(Zorin et al., 1999)

lix

(Silva et al., 1991)

Nrg

(Kerr et al., 1997, Bieber et al., 1989, King et al., 1986)

(van den Dries et al., 1996, Harbecke and Lengyel, 1995, Tearle and Nusslein-Volhard, 1987, Craymer and Roy, 1980)

otu

(Geyer et al., 1993, Pauli et al., 1993)

(King et al., 1986)

ptg

(Craymer and Roy, 1980)

sdt

(Harbecke and Lengyel, 1995, Tearle and Nusslein-Volhard, 1987)

Smox

(Zheng et al., 2003)

wiser

(Mela et al., 2009)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

(Proust et al., 1992, Eeken et al., 1985)

dec

(Lineruth et al., 1985)

fs(1)h

(Zheng et al., 2003, Florence and McGinnis, 1998, Eeken et al., 1985)

fs(1)M122

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Da

(Henderson and Andrew, 1998, Schalet, 1986)

l(1)7Dc

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7Dd

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7De

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)7DEa

(Schalet, 1986)

l(1)7Df

(Zheng et al., 2003, Henderson and Andrew, 1998)

l(1)B23.2

(Proust et al., 1992)

l(1)D39.5

(Proust et al., 1992)

l(1)ESHS24

(Eeken et al., 1985)

l(1)ESHS25

(Eeken et al., 1985)

l(1)ESHS26

(Eeken et al., 1985)

l(1)ESHS27

(Eeken et al., 1985)

l(1)ESHS28

(Eeken et al., 1985)

l(1)ESHS29

(Eeken et al., 1985)

l(1)ESHS30

(Eeken et al., 1985)

l(1)ESHS31

(Eeken et al., 1985)

l(1)ESHS32

(Eeken et al., 1985)

l(1)ESHS33

(Eeken et al., 1985)

l(1)ESHS34

(Eeken et al., 1985)

l(1)ESHS35

(Eeken et al., 1985)

l(1)ESHS36

(Eeken et al., 1985)

l(1)ESHS37

(Eeken et al., 1985)

mys

(Zheng et al., 2003, Henderson and Andrew, 1998)

rdgA

(Harris and Stark, 1977)

sesB

(Rikhy et al., 2003)

(Zheng et al., 2003, Henderson and Andrew, 1998, Eeken et al., 1985)

tx-like

(Florence, 1999.7.22)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

The viability of Df(1)svr/Df(1)RA2 or Df(1)svr/+ female progeny derived from a cross between Df(1)RA2/+ females and Df(1)svr/Y males is severely reduced. The viability of Df(1)N71/Df(1)RA2 or Df(1)N71/+ female progeny derived from a cross between Df(1)RA2/+ females and Df(1)N71/Y males is severely reduced.

(Sanchez et al., 1994)

Fails to complement Df(1)D46.

(Eeken et al., 1985)

Df(1)RA2/Ubl females slight oc phenotype

NOT in combination with other aberrations

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 25-75%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Homozygous embryos are very abnormal compared to wild-type.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxl^f1. Female lethality is also reduced when in combination with da¹ but restored when in combination with emc^ML.

(Anand and Chandra, 1994)

The viability of Sxl^f1/Df(1)RA2 female progeny derived from a cross between Df(1)RA2/+ females and Sxl^f1/Y males is severely reduced. Viability is recovered if the Sxl^f1/Df(1)RA2 female progeny also carry Dp(1;3)sn^13a1 or if the Df(1)RA2/+ mothers also carry Dp(1;3)sn^13a1.

(Sanchez et al., 1994)

Heterozygotes have ocelli placed far back on the head and there is a slight indentation in the cuticle beneath the postvertical bristles.

(Craymer and Roy, 1980)

Stocks (2)

950

108929

Notes on Origin

Discoverer

Lefevre.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"7D18--22;8A4--5" was stated as revision. Complements Df(1)Desi-S3.

(Dorer et al., 1993)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

950

(Rikhy et al., 2003)

Df RA2

(Proust et al., 1992)

Df(1)950

(Mela et al., 2009)

Df(1)RA

(Prudhommeau and Proust, 1990)

Df(1)RA2

(Cherezov et al., 2020, Denef et al., 2008, Crest et al., 2007, Shima et al., 2007, Carhan et al., 2005, Korey and MacDonald, 2003)

Df(1)oc-RA2

Df(2L)RA2

(Tearle and Nusslein-Volhard, 1987)

RA2

(Sanchez et al., 1994)

Name Synonyms

Secondary FlyBase IDs

FBab0022119

References (64)

Report Sections

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