Only male progeny are recovered from da1/dak08611 females.
Homozygotes survive at 18oC and die at 25oC. da1 homozygous embryos lacking maternal and zygotic da have defects in mesodermal development. The mesoderm migrates properly, however, further mesodermal development is impaired. Somatic muscle development is severely suppressed, embryos have reduced numbers of aberrantly placed syncitial muscles. Heart development is also repressed.
Homozygous females have no female offspring due to failure to properly regulate the Sxl gene in the zygote.
At the restrictive temperature (25oC) less than 1% of females derived from homozygous mothers eclose. At the permissive temperature (18oC) the viability of these females derived from homozygous mothers is 100%.
Sxlf1 heterozygous female progeny derived from heterozygous da1 mothers have reduced viability. The viability is increased if the Sxlf1/+ progeny are also carrying msl-31, and is decreased if the da1/+ mothers are also carrying msl-31. The frequency of sex transformation in Sxlf1/+ female progeny derived from da1/+ mothers is increased if either the mothers or the progeny are homozygous for msl-31. The frequency of morphological abnormalities seen in Sxlf1/+ female progeny derived from da1/+ mothers is greatly reduced if the progeny are also homozygous for msl-31.
Homozygous females when mated to any male produce normal sons but no daughters. Otherwise, da mutant cannot be distinguished from wild type.
(=da); viable; temperature-sensitive hypomorph; strong daughterless maternal effect above 22oC; lethal with Df or amorphic alleles; lethal at 29oC