FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ensΔN
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General Information
Symbol
Dmel\ensΔN
Species
D. melanogaster
Name
FlyBase ID
FBal0230193
Feature type
allele
Associated gene
Dmel\ens
Associated Insertion(s)
Carried in Construct
Also Known As
enscΔN
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Sung et al., 2008)
Progenitor genotype
P{RS3}ensCB-5457-3
(Sung et al., 2008)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion of ens sequences from +31 to +1475 relative to the transcription start site.

(Sung et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:4,133,075..4,134,519 [-]
Comment:

A 1445 bp deletion generated by the imprecise excision that maps to +31 to +1475 relative to the ens transcription start site that removes the first two exons of ens.

(Sung et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most ensΔN/Df(3L)ensΔ3277 larval brain neuroblasts exhibit incomplete centrosome separation before mitosis when compared to controls. ensΔN/Df(3L)ensΔ3277 third instar larval brain neuroblasts exhibit shorter mitotic spindles compared to controls.

      ensΔN/Df(3L)ensΔ3277 oocytes fail to exhibit ooplasmic streaming compared to controls.

      (Métivier et al., 2019)

      ensΔN fails to complement the myonuclear positioning defect of ensswo.

      (Metzger et al., 2012)

      Eggs laid by homozygous females sometimes have dorsal appendages that are close together or fused.

      (Sung et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ensΔN
      (Gallaud et al., 2014, Metzger et al., 2012, Sung et al., 2008)
      enscΔN
      (Thomas et al., 2021, Métivier et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)