FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\marsRNAi.UAS.WIZ
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General Information
Symbol
Dmel\marsRNAi.UAS.WIZ
Species
D. melanogaster
Name
FlyBase ID
FBal0230463
Feature type
allele
Associated gene
Dmel\mars
Associated Insertion(s)
Carried in Construct
P{UAS-mars.RNAi.WIZ}
Also Known As
pWIZ-mars-RNAi
Key Links
Transgenic product class
RNAi_reagent
(Yang et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Yang et al., 2005)
Mutagen
in vitro construct
(Yang et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-mars.RNAi.WIZ}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of a 484bp fragment corresponding to positions 231-969 of the mars coding sequence.

(Yang et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mars
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The number of mitotic cells in the second mitotic wave is significantly increased in third instar larval eye discs expressing marsScer\UAS.WIZ under the control of Scer\GAL4tub. This increase is due to an increase in the number of prometaphase and metaphase cells.

      (Yang and Fan, 2008)

      Flies expressing marsScer\UAS.WIZ under the control of Scer\GAL4GMR.PF do not have a mutant eye phenotype.

      Flies expressing marsScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF have small, rough eyes. This phenotype is partially suppressed by coexpression of marsScer\UAS.WIZ.

      The number of mitotic cells at the second mitotic wave in eye discs expressing marsScer\UAS.WIZ under the control of Scer\GAL4GMR.PF is not significantly different from that of controls.

      The fraction of mitotic cells in anaphase or telophase in eye discs expressing marsScer\UAS.WIZ under the control of Scer\GAL4GMR.PF is not significantly different from that of controls.

      The pattern of apoptotic cells in eye discs expressing marsScer\UAS.WIZ under the control of Scer\GAL4GMR.PF is not significantly different from that of controls.

      (Yang et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      marsRNAi.UAS.WIZ
      marsScer\UAS.WIZ
      marsdsRNA.Scer\UAS.WIZ
      marsdsRNA.UAS.WIZ
      Name Synonyms
      Secondary FlyBase IDs
        References (3)