FlyBase Allele Report: Dmel\Cul1[KK100827]

General Information

Symbol

Dmel\Cul1^KK100827

Species

D. melanogaster

Name

FlyBase ID

FBal0230938

Feature type

allele

Associated gene

Dmel\Cul1

Associated Insertion(s)

Carried in Construct

P{KK100827}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK100827}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK100827

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^GMR.PU

(Bhutani et al., 2012)

visible, with Scer\GAL4^GMR.PU

(Bhutani et al., 2012)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Bhutani et al., 2012)

Detailed Description

Statement

Reference

Flies expressing lin19^KK100827 under the control of Scer\GAL4^GMR.PU have a slight rough eye phenotype.

(Bhutani et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Cul1^KK100827/Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Bhutani et al., 2012)

Cul1^KK100827, Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Scer\GAL4^GMR.PU, Zzzz\CAG^{127Q.UAS.Tag:HA}

(Bhutani et al., 2012)

Other

Statement

Reference

Cul1^KK100827, Scer\GAL4^GMR.PU, Zzzz\CAG^{127Q.UAS.Tag:HA} has lethal phenotype

(Bhutani et al., 2012)

Cul1^KK100827, Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^GMR.PU has lethal phenotype

(Bhutani et al., 2012)

Cul1^KK100827, Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^GMR.PU has visible phenotype

(Bhutani et al., 2012)

Cul1^KK100827, Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PU has lethal phenotype

(Bhutani et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Cul1^KK100827/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Bhutani et al., 2012)

Cul1^KK100827, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\CAG^{127Q.UAS.Tag:HA}

(Bhutani et al., 2012)

Other

Statement

Reference

Cul1^KK100827, Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^GMR.PU has eye phenotype

(Bhutani et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108558

P{KK100827}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Cul1^KK100827

lin19^KK100827

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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