FlyBase Allele Report: Dmel\eIF6[KK101259]

General Information

Symbol

Dmel\eIF6^KK101259

Species

D. melanogaster

Name

FlyBase ID

FBal0231154

Feature type

allele

Associated gene

Dmel\eIF6

Associated Insertion(s)

Carried in Construct

P{KK101259}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101259}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101259

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | spermatogenesis, with Scer\GAL4^tj.PU

(Wang et al., 2025)

partially lethal, with Scer\GAL4^Dll-md23

(Grubbs et al., 2013)

some die during pupal stage, with Scer\GAL4^Dll-md23

(Grubbs et al., 2013)

Phenotype Manifest In

cyst progenitor cell | ectopic, with Scer\GAL4^tj.PU

(Wang et al., 2025)

sex comb, with Scer\GAL4^Dll-md23

(Grubbs et al., 2013)

tarsal segment, with Scer\GAL4^Dll-md23

(Grubbs et al., 2013)

Detailed Description

Statement

Reference

Animals expressing eIF6^KK101259 under the control of Scer\GAL4^Dll-md23 lack tarsi and have reduced sex combs.

(Grubbs et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^da.PU/eIF6^KK101259 is a suppressor | partially of increased mortality during development phenotype of Sbds^f01686

(Tan et al., 2021)

Scer\GAL4^da.PU/eIF6^KK101259 is a suppressor of abnormal developmental rate | larval stage phenotype of Sbds^f01686

(Tan et al., 2021)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v108094

P{KK101259}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

eIF6^KK101259

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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