FlyBase Allele Report: Dmel\VGAT[KK101500]

General Information

Symbol

Dmel\VGAT^KK101500

Species

D. melanogaster

Name

FlyBase ID

FBal0231310

Feature type

allele

Associated gene

Dmel\VGAT

Associated Insertion(s)

Carried in Construct

P{KK101500}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101500}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101500

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior, with Scer\GAL4^5-HT1B.PY

(Yuan et al., 2014)

abnormal touch perception | adult stage, with Scer\GAL4^GMR41E11

(Jeong et al., 2016)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of VGAT^KK101500 (together with UAS-Dicer2 to enhance RNAi efficiency) under the control of Scer\GAL4^GMR41E11 results in defects in sensing food hardness as the flies show diminished preference for softer food to harder food (at the expense of sweetness) compared to controls.

(Jeong et al., 2016)

Expression of VGAT^KK101500 under the control of Scer\GAL4^dimm-929 does not affect sensitivity to (S,Z,Z)-CH503 (a more potent stereoisomer of the gustatory sex pheromone CH503). As in wild type flies, courtship defects are seen in response to (S,Z,Z)-CH503.

(Shankar et al., 2015)

Expression of VGAT^KK101500 under the control of Scer\GAL4^5-HT1B.PY impairs the inhibition of female contact-induced male-male aggression seen in wild type males that have previously been exposed to females.

(Yuan et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v103586

P{KK101500}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG8394^KK101500

VGAT^KK101500

Vgat^KK

(Jeong et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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