FlyBase Allele Report: Dmel\Usp47[KK102376]

General Information

Symbol

Dmel\Usp47^KK102376

Species

D. melanogaster

Name

FlyBase ID

FBal0231756

Feature type

allele

Associated gene

Dmel\Usp47

Associated Insertion(s)

Carried in Construct

P{KK102376}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102376}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102376

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

abnormal locomotor behavior | adult stage, with Scer\GAL4^sqh.PW

(Tsou et al., 2012)

increased mortality during development | conditional, with Scer\GAL4^da.PU

(Páhi et al., 2022)

radiation sensitive | third instar larval stage, with Scer\GAL4^da.PU

(Páhi et al., 2022)

short lived, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

short lived, with Scer\GAL4^sqh.PW

(Tsou et al., 2012)

visible | adult stage, with Scer\GAL4^Bx-MS1096

(Shi et al., 2015)

Phenotype Manifest In

wing | progressive, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

wing margin bristle, with Scer\GAL4^Bx-MS1096

(Shi et al., 2015)

Detailed Description

Statement

Reference

The expression of Usp47^KK102376 under the control of Scer\GAL4^da.PU leads to third instar larvae showing increased sensitive to UV radiation.

(Páhi et al., 2022)

Expression of Usp47^KK102376 RNAi under the control of Scer\GAL4^Bx-MS1096 results in wing margin bristle defects.

(Shi et al., 2015)

Most Scer\GAL4^sqh.PW, Ubp64E^KK102376 flies die soon after eclosion; others are dead by 20 days and adults are slower than controls.

Most Scer\GAL4^elav.PU, Ubp64E^KK102376 flies die soon after eclosion; others are dead by 40 days and adults are slower than controls.

No phenotype is observed when Ubp64E^KK102376 is expressed using Scer\GAL4^repo.

Expression of Ubp64E^KK102376 using Scer\GAL4^sqh.PW or Scer\GAL4^elav.PU results in a progressive drooping wing phenotype.

(Tsou et al., 2012)

Expression of Ubp64E^KK102376 under the control of Scer\GAL4^bbg-C96 does not result in a wing phenotype.

Expression of Ubp64E^KK102376 under the control of Scer\GAL4^dpp.PU does not result in a bristle phenotype.

(Zhang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v103743

P{KK102376}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ubp64E^KK102376

Usp47^KK102376

Usp47ⁱ¹

(Kassel et al., 2023)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

Open Close