FlyBase Allele Report: Dmel\qua[KK103765]

General Information

Symbol

Dmel\qua^KK103765

Species

D. melanogaster

Name

FlyBase ID

FBal0232518

Feature type

allele

Associated gene

Dmel\qua

Associated Insertion(s)

Carried in Construct

P{KK103765}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK103765}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK103765

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

decreased size | larval stage, with Scer\GAL4^ap-md544

(Hurbain et al., 2022)

decreased size | larval stage, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

Phenotype Manifest In

epithelial cell of wing disc, with Scer\GAL4^ap-md544

(Hurbain et al., 2022)

epithelial cell of wing disc, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

extracellular vesicle | decreased number | larval stage, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

microvillus | decreased number | larval stage, with Scer\GAL4^ap-md544

(Hurbain et al., 2022)

microvillus | decreased number | larval stage, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

wing, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

wing disc, with Scer\GAL4^ap-md544

(Hurbain et al., 2022)

wing disc, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

wing pouch, with Scer\GAL4^ap-md544

(Hurbain et al., 2022)

wing pouch, with Scer\GAL4^hh-Gal4

(Hurbain et al., 2022)

Detailed Description

Statement

Reference

The expression of qua^KK103765 under the control of Scer\GAL4^hh-Gal4 or Scer\GAL4^ap-md544 induces a small wing disc pouch, as well as fewer and shortened/misshapen in microvilli in the wing disc posterior compartment. In the Scer\GAL4^hh-Gal4-driven expression condition, wing discs show a decrease in the number of extracellular vesicle; adults show a small wing.

(Hurbain et al., 2022)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100856

P{KK103765}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

qua^KK103765

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close