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General Information
Symbol
Dmel\FASN1KK107330
Species
D. melanogaster
Name
FlyBase ID
FBal0234870
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-FAS-RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Animals expressing CG3523KK107330 under the control of Scer\GAL4αTub84B.PL show early larval lethality on a 20% yeast diet, but supplementation of the diet with 15% sucrose partially rescues the lethality, allowing pupation.

Expression of CG3523KK107330 under the control of Scer\GAL4Bx-MS1096 results in slight curling of the wing.

Expression of CG3523KK107330 under the control of Scer\GAL4Lsp2.PH partially rescues the increase in triglyceride levels and the heart defects normally caused by a high-fat diet.

Expression of CG3523KK107330 under the simultaneous control of both Scer\GAL4Scer\UAS.cHa and Scer\GAL4tin.cBa does not rescue the increase in triglyceride levels caused by a high-fat diet. However, the heart defects normally caused by a high-fat diet are rescued in these animals.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

The increased triglyceride levels seen in the hearts of 1 week old eas2 females are suppressed if they are also expressing CG3523KK107330 under the control of Scer\GAL4HCH.Hand.

Expression of CG3523KK107330 under the control of Scer\GAL4HCH.Hand rescues the increased heartbeat rate, constricted heart phenotype and muscle defects of eas2 flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG3523KK107330
FASN1KK107330
Name Synonyms
Secondary FlyBase IDs
    References (7)