FB2026_02 , released June 18, 2026
Allele: Dmel\Wbp2KK108304
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General Information
Symbol
Dmel\Wbp2KK108304
Species
D. melanogaster
Name
FlyBase ID
FBal0235487
Feature type
allele
Associated gene
Dmel\Wbp2
Associated Insertion(s)
Carried in Construct
P{KK108304}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK108304}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK108304
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4hh.PU-mediated expression of Wbp2KK108304 produces wings with scalloped edges that are reduced in size.

      (Zhang et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Wbp2KK108304/Scer\GAL4αTub84B.PL is a suppressor of lethal | somatic clone phenotype of wtsx1

      (Zhang et al., 2011)
      NOT Suppressor of
      Statement
      Reference

      Wbp2KK108304/Scer\GAL4αTub84B.PL is a non-suppressor of abnormal size | somatic clone phenotype of Tsc1Q87X

      (Zhang et al., 2011)
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Wbp2KK108304/Scer\GAL4αTub84B.PL is a non-suppressor of eye | somatic clone phenotype of Tsc1Q87X

      (Zhang et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When Wbp2KK108304 is expressed in wtsx1-deficient tissues using eyFlp/MARCM, a significant increase in survival is observed with the majority of flies now reaching late pupal stages and forming pharate adults, with a small number emerging as fully developed adults.

      When Wbp2KK108304 is expressed in wtsx1-deficient tissues using eyFlp/MARCM, eye disc size is reduced, the amount of wtsx1 tissue relative to wild type tissue is decreased, and the differentiation of the developing eye is almost completely restored.

      Eyes remain overgrown when Wbp2KK108304 is expressed in Tsc1Q87X-deficient eyes using eyFlp/MARCM.

      (Zhang et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG11009KK108304
      Wbp2KK108304
      Name Synonyms
      Secondary FlyBase IDs
        References (2)