Expression of CASK^KK109311 under the control of Scer\GAL4^VGlut-OK371 results in an increase in bouton number/area for type Ib boutons at the larval neuromuscular junction, while bouton area is normal.

Expression of CASK^KK109311 under the control of Scer\GAL4^Mef2.PR results in a decrease in bouton area for type Ib boutons at the larval neuromuscular junction, while bouton number/area is normal.

Flies expressing CASK^KK109311 under the control of Scer\GAL4^Tab2-201Y show a reduced performance index in an appetitive associative learning assay compared to wild type.

Flies expressing CASK^KK109311 under the control of either Scer\GAL4^ey-OK107, Scer\GAL4^c305a or Scer\GAL4^Mef2.247 or Scer\GAL4^CaMKII.7 show normal learning (measured as 2 minute memory) in an olfactory aversive conditioning assay.

Flies expressing CASK^KK109311 under the control of either Scer\GAL4^ey-OK107 or Scer\GAL4^c305a show a severe reduction in middle-term memory (measured 3 hours after one cycle of training) in an olfactory aversive conditioning assay. This defect is still seen if expressed is limited to the adult stage using the temperature-sensitive Scer\GAL80^ts.αTub84B allele.

Flies expressing CASK^KK109311 under the control of Scer\GAL4^Mef2.247 show normal middle-term memory (measured 3 hours after one cycle of training) in an olfactory aversive conditioning assay.

Expression of CASK^KK109311 under the control of Scer\GAL4^CaMKII.7 completely removes middle-term memory (measured 3 hours after one cycle of training) in an olfactory aversive conditioning assay.

Flies expressing CASK^KK109311 under the control of either Scer\GAL4^ey-OK107 or Scer\GAL4^c305a have no long-term memory (measured 24 hours after 5 cycles of spaced training) in an olfactory aversive conditioning assay.

Flies expressing CASK^KK109311 under the control of Scer\GAL4^Mef2.247 show normal long-term memory (measured 24 hours after 5 cycles of spaced training) in an olfactory aversive conditioning assay.

Flies expressing CASK^KK109311 under the control of either Scer\GAL4^ey-OK107 or Scer\GAL4^c305a have significantly reduced anesthesia-resistant memory (measured 24 hours after 5 cycles of massed training) in an olfactory aversive conditioning assay.

Flies expressing CASK^KK109311 under the control of Scer\GAL4^Mef2.247 show normal anesthesia-resistant memory (measured 24 hours after 5 cycles of massed training) in an olfactory aversive conditioning assay.