FlyBase Allele Report: Dmel\TpnC4[KK110436]

General Information

Symbol

Dmel\TpnC4^KK110436

Species

D. melanogaster

Name

FlyBase ID

FBal0236857

Feature type

allele

Associated gene

Dmel\TpnC4

Associated Insertion(s)

Carried in Construct

P{KK110436}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK110436}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK110436

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal jump response, with Scer\GAL4^Act79B.PB

(Chechenova et al., 2017)

flightless, with Scer\GAL4¹¹⁵¹

(Chechenova et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of TpnC4^KK110436 results in decreased jumping ability (with the Scer\GAL4^Act79B.PB driver) and loss of the ability to fly (with Scer\GAL4¹¹⁵¹ driver).

(Chechenova et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^Act79B.PB, TpnC4^KK110436 has abnormal jump response phenotype, enhanceable by Scer\GAL4^Act88F.PB/TpnC41C^JF02379/Scer\GAL4^Act79B.PB

(Chechenova et al., 2017)

Enhancer of

Statement

Reference

TpnC4^KK110436, Scer\GAL4^Act88F.PB, Scer\GAL4^Act79B.PB is an enhancer of abnormal jump response phenotype of Scer\GAL4^Act79B.PB, TpnC41C^JF02379

(Chechenova et al., 2017)

Other

Statement

Reference

Scer\GAL4^Act79B.PB, Scer\GAL4^Act88F.PB, TpnC41C^JF02379, TpnC4^KK110436 has abnormal flight phenotype

(Chechenova et al., 2017)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Adult flies expressing both TpnC41C^JF02379 and TpnC4^KK110436 simultaneously under the combined control of Scer\GAL4^Act79B.PB and Scer\GAL4^Act88F.PB cannot jump and display severe flight defects with the majority of animals being completely flightless.

(Chechenova et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v102031

P{KK110436}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

TpnC4^KK110436

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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