FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mib2C935S-C1020S.UAS
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General Information
Symbol
Dmel\mib2C935S-C1020S.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0239050
Feature type
allele
Associated gene
Dmel\mib2
Associated Insertion(s)
Carried in Construct
P{UAS-mib2.C935S-C1020S}
Key Links
Transgenic product class
missense_variant
(Carrasco-Rando and Ruiz-Gómez, 2008)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Carrasco-Rando and Ruiz-Gómez, 2008)
Mutagen
in vitro construct
(Carrasco-Rando and Ruiz-Gómez, 2008)
Progenitor genotype
Carried in construct
P{UAS-mib2.C935S-C1020S}
Cytology
Description

Amino acid replacement: C935S.

(Carrasco-Rando and Ruiz-Gómez, 2008)

UAS regulatory sequences drive expression of a mutated form of mib2.

(Carrasco-Rando and Ruiz-Gómez, 2008)

Amino acid replacement: C1020S.

(Carrasco-Rando and Ruiz-Gómez, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mib2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of mib2C935S-C1020S.Scer\UAS under the control of Scer\GAL4Mef2.PR does not result in myoblast fusion defects in embryos.

      (Carrasco-Rando and Ruiz-Gómez, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4how-24B/mib2C935S-C1020S.UAS partially rescues mib21

      (Carrasco-Rando and Ruiz-Gómez, 2008)
      Comments

      Expression of mib2C935S-C1020S.Scer\UAS under the control of Scer\GAL4how-24B does not rescue the myoblast fusion defect of mib21 embryos, but rescues the other embryonic phenotypes (detachment phenotype, sarcomeric organisation and, to a large extent, the visceral muscle defects, since all but the first gut constriction are formed).

      (Carrasco-Rando and Ruiz-Gómez, 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mib2C935S-C1020S.Scer\UAS
      mib2C935S-C1020S.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)