FB2026_02 , released June 18, 2026
Allele: Dmel\p1130EP1130
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General Information
Symbol
Dmel\p1130EP1130
Species
D. melanogaster
Name
FlyBase ID
FBal0239054
Feature type
allele
Associated gene
p1130
Associated Insertion(s)
P{EP}p1130EP1130
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}p1130EP1130
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant males and females show an increase in mean survival compared to control flies under the multiple-stress paradigm of 10mM paraquat and wet starvation.

        Mutant males and females show a mean lifespan enhancement of 38% and 22% respectively compared to control flies and a 15% maximum lifespan extension for both sexes. The mutant flies are longer lived than controls under both abundant and restricted food conditions.

        The mutant flies show no difference in food uptake or metabolic rate (as measured by carbon dioxide output) compared to controls. The mutant flies show a slight increased in fecundity and show enhanced climbing ability compared to controls.

        (Liu et al., 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        p1130EP1130/α-Man-IEP1628 and p1130EP1130/α-Man-IEP982 flies have similar lifespan profiles as α-Man-IEP982/α-Man-IEP1628 flies.

        (Liu et al., 2009)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        p1130EP1130
        Name Synonyms
        Secondary FlyBase IDs
          References (1)