FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(spl)mα-BFMD.UAS
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General Information
Symbol
Dmel\E(spl)mα-BFMD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0239185
Feature type
allele
Associated gene
Dmel\E(spl)mα-BFM
Associated Insertion(s)
Carried in Construct
P{UAS-E(spl)mα-BFM.D}
Key Links
Transgenic product class
stop_gained
(Fontana and Posakony, 2009)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Fontana and Posakony, 2009)
Mutagen
in vitro construct
(Fontana and Posakony, 2009)
Progenitor genotype
E(spl)mα-BFMUAS.cFa
(Fontana and Posakony, 2009)
Carried in construct
P{UAS-E(spl)mα-BFM.D}
Cytology
Description

A stop codon has been introduced just N-terminal to the D motif (DRWAQA) normally found at the C-terminus of mα.

(Fontana and Posakony, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
E(spl)mα-BFM
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mαD.Scer\UAS under the control of Scer\GAL4sca-537.4 results in the production of extra bristles (average 6.5 extra bristles per fly, total of 26 bristle positions on the notum and head assayed).

      (Fontana and Posakony, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E(spl)mα-BFMD.Scer\UAS
      E(spl)mα-BFMD.UAS
      mαD.Scer\UAS
      mαD
      (Fontana and Posakony, 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)