FlyBase Allele Report: Dmel\Sans[245]

General Information

Symbol

Dmel\Sans²⁴⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0239910

Feature type

allele

Associated gene

Dmel\Sans

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Demontis and Dahmann, 2009)

Progenitor genotype

P{EP}Sans^GE10371

(Demontis and Dahmann, 2009)

Caused by aberration

Df(2R)Sans²⁴⁵

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of the Sans gene and also affects the CG30487 gene (gene on opposite strand within an intron of Sans). The deletion is of 1331bp, spanning from nucleotide 122367 to nucleotide 123696 of the genomic sequence AE003820.

(Demontis and Dahmann, 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2R:12,938,133..12,939,462 [+]

Comment:

1331 bp deletion resulting from the imprecise excision of P{EP}SansGE10371 effects both Sans and CG30487, which maps to an intron of Sans.

(Demontis and Dahmann, 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female fertile

(Demontis and Dahmann, 2009)

male fertile

(Demontis and Dahmann, 2009)

viable

(Demontis and Dahmann, 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Flies bearing Sans²⁴⁵ mutant clones in the Johnston's organ do not exhibit any defects in the attachment of scolopidia to the hinge of the second and third antennal segment.

(Li et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Sans²⁴⁵/Sans[+] is an enhancer of Johnston organ | P-stage | somatic clone phenotype of Ubr3^B

(Li et al., 2016)

Sans²⁴⁵/Sans[+] is an enhancer of scolopidium | P-stage | somatic clone phenotype of Ubr3^B

(Li et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

The scolopidia detachment phenotype observed in Ubr3^B mutant clones in the pupal Johnston's organ is significantly enhanced by combination with a single copy of Sans²⁴⁵.

(Li et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

67201

P{neoFRT}42D Sans²⁴⁵

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Sans²⁴⁵

(Demontis and Dahmann, 2009)

sans²⁴⁵

(Li et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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