FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Taf34
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General Information
Symbol
Dmel\Taf34
Species
D. melanogaster
Name
FlyBase ID
FBal0239939
Feature type
allele
Associated gene
Dmel\Taf3
Associated Insertion(s)
TI{TI}Taf34
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gene targeting by homologous recombination
(Prince et al., 2008)
Progenitor genotype
Associated Insertion(s)
TI{TI}Taf34
Cytology
Description

1.2kb deletion from -1.1kb to +152bp relative to the bip2 translation start codon, deleting the first exon harbouring the Histone Fold Domain. A w+mW.hs marker (originating from the pTV2-based donor construct) is also present.

(Prince et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      bip24 mutants are late embryonic or first instar larval recessive lethal, without any obvious morphological defects.

      (Prince et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      bip2[+]/Taf34 is an enhancer of eye phenotype of AntpCtx

      (Prince et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Approximately 4% in AntpCtx/+;bip24/+ transheterozygous flies. Flies showing an ectopic wing on the head almost always show a normal or slightly reduced eye, whereas flies with a head capsule-to-thorax transformation mostly have reduced or lost eyes.

      AntpCtx/+;bip24/+ flies show strong eye-reduction/eye-loss phenotypes. Thirty-four percent of the eyes of AntpCtx/+;bip24/+ flies show an eye-loss phenotype, compared with 2% without the bip24 mutation.

      (Prince et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Taf34
      bip24
      (Prince et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)