FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TgNIG.7356R
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General Information
Symbol
Dmel\TgNIG.7356R
Species
D. melanogaster
Name
FlyBase ID
FBal0239959
Feature type
allele
Associated gene
Dmel\Tg
Associated Insertion(s)
Carried in Construct
P{NIG.7356R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Lindgren et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Lindgren et al., 2008)
Mutagen
in vitro construct
(Lindgren et al., 2008)
Progenitor genotype
Carried in construct
P{NIG.7356R}
Cytology
Description

UASt regulatory sequences drive expression of a Tg RNAi construct.

(Lindgren et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-7356R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Parkinson's disease 6
      modeled by Pink1UAS.Tag:HA
      (Min et al., 2015)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of TgNIG.7356R driven by Scer\GAL4GMR.PU does not result in a significant rough eye phenotype.

      (Min et al., 2015)

      The eclosion rate of animals expressing TgNIG.7356R under the control of Scer\GAL4da.G32 is approximately 20% that of controls. After eclosion, approximately 90% of the adults show abnormal cuticle morphology in the wings and the abdominal tergites; the wings fail to expand properly, resulting in blistering, and several melanized segments on the abdominal tergites fail to develop. Adults expressing TgNIG.7356R under the control of Scer\GAL4da.G32 have a shorter lifespan than controls, with approximately 90% dying within 30 days of eclosion.

      (Shibata et al., 2010)

      Larvae expressing TgNIG.7356R under the control of Scer\GAL4Act5C show a reduced clot fibre length (assayed by drawout using a fine needle of clot strands from hemolymph bled from larvae into Ringer's solution) compared to control larvae.

      (Lindgren et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      TgNIG.7356R, Scer\GAL4GMR.PU is a suppressor | partially of visible phenotype of Pink1UAS.Tag:HA, Scer\GAL4GMR.PU

      (Min et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      TgNIG.7356R, Scer\GAL4GMR.PU is a suppressor | partially of eye phenotype of Pink1UAS.Tag:HA, Scer\GAL4GMR.PU

      (Min et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of TgNIG.7356R partially suppresses the rough eye phenotype seen in flies with Pink1Scer\UAS.T:Ivir\HA1 driven by Scer\GAL4GMR.PU.

      (Min et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG7356NIG.7356R
      TgNIG.7356R
      Name Synonyms
      Secondary FlyBase IDs
        References (5)