FlyBase Allele Report: Dmel\defl[Z]

Extimated boundaries of a 702 bp deletion resulting from the imprecise excision of P{EP}Naa60^EP3301. The deletion extends in both directions from the insertion site and removes the 3' end of defl. Sequence encoding the first 986 aa of defl remains.

(Rutkowski and Warren, 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dorsal appendage | maternal effect (with defl^L)

(Rutkowski and Warren, 2009)

dorsal appendage | maternal effect (with defl^P)

(Rutkowski and Warren, 2009)

egg chorion | maternal effect (with defl^L)

(Rutkowski and Warren, 2009)

egg chorion | maternal effect (with defl^P)

(Rutkowski and Warren, 2009)

Detailed Description

Statement

Reference

60% of defl^P/defl^Z animals and 18% of defl^L/defl^Z and defl^Z/Df(3L)defl^Δ animals survive to adulthood. 80% of the defl^P/defl^Z escapers and 100% of defl^L/defl^Z escapers are male.

40% of eggs laid by defl^P/defl^Z females and 64% of eggs laid by defl^L/defl^Z females have defective chorion and dorsal appendage formation. The frequency of morphologically normal eggs that hatch is only 3% for eggs laid by defl^P/defl^Z females.

defl^Z/Df(3L)defl^Δ females lay very few eggs.

(Rutkowski and Warren, 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

defl^L

(Rutkowski and Warren, 2009)

defl^P

(Rutkowski and Warren, 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: A closely linked second site lethal mutation.

(Rutkowski and Warren, 2009)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

defl^Z

(Rutkowski and Warren, 2009)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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