pim promoter sequences drive expression of a mutated pim ORF and 3'UTR; the destruction box has been mutated from KKPLGNLDN to AKPAGNLDA and the KEN motif found near the N-terminal end of the coding sequence has been mutated to AAA. Generated by excision of the FRT stop cassette from pimkenadba.g.FRT.
pimkenadba.g fails to rescue pimIL
Inhibition of sister chromatid separation during mitosis 15 in pimIL/pimIL embryos (from pimIL/+ mothers) is not rescued by pimkenadba.g.