FB2026_03 , released September 17, 2026
Allele: Dsim\DoxΔ105
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General Information
Symbol
Dsim\DoxΔ105
Species
D. simulans
Name
FlyBase ID
FBal0240568
Feature type
allele
Associated gene
Dsim\Dox
Associated Insertion(s)
Carried in Construct
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Tao et al., 2007)
Mutagen
natural population
(Tao et al., 2007)
Progenitor genotype
Cytology
Description

Deletion of 105bp, resulting in the loss of exon III, which deletes one of the 42bp elements that is tandemly repeated in wild-type Dsim\Dox.

(Tao et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The sex ratio of progeny derived from Dsim\DoxΔ105 males is 54% and no abnormal spermatid heads are seen.

      (Tao et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dsim\DoxΔ105 Dsim\Nmy1427 males do not show sex ratio distortion (the sex ratio of the progeny of double mutant males raised at 16[o]C is 54%). All stages of spermatid maturation appear to be normal in these double mutant males.

      (Tao et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dsim\DoxΔ105
      dox
      (Tao et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)