FB2026_02 , released June 18, 2026
Allele: Dmel\ec3c3
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General Information
Symbol
Dmel\ec3c3
Species
D. melanogaster
Name
FlyBase ID
FBal0240686
Feature type
allele
Associated gene
Dmel\ec
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Copeland et al., 2007)
Mutagen
ethyl methanesulfonate
(Copeland et al., 2007)
Progenitor genotype
Cytology
Description

Amino acid replacement: L792term.

(Copeland et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:3,853,731..3,853,731 [+]
Nucleotide change:

T3853731G

Amino acid change:

L762term | ec-PA; L796term | ec-PB; L815term | ec-PC

Reported amino acid change:

L792term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. There is no L at residue 792 in ec splice form 1 as reported. The mutation was mapped to the nearest L residue that can change to a stop with one base change.

(Copeland et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous adults have rough eyes and extra interommatidial cells are present in the pupal retina.

      ec3c3/Df(1)HC244 adults have a stronger rough eye phenotype than ec3c3 homozygotes.

      (Copeland et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ec3c3
      (Copeland et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)