FB2026_02 , released June 18, 2026
Allele: Dmel\Inx5JF02877
Open Close
General Information
Symbol
Dmel\Inx5JF02877
Species
D. melanogaster
Name
FlyBase ID
FBal0240846
Feature type
allele
Associated gene
Dmel\Inx5
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02877}
Also Known As
UAS-Inx5-RNAi, JF02877, inx5 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF02877}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02877
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Inx5JF02877 under the control of Scer\GAL4ey-OK107 in adults significantly reduces 3 hour aversive olfactory memory and the residual anaesthesia-resistant memory (ARM) after cold-shock, compared to controls; there is no effect on short-term memory or the anaesthesia-sensitive component of 3 hour memory, compared to controls. Expression under the control of Scer\GAL4VT049246, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, also significantly reduces 3 hour aversive olfactory ARM, compared to controls, with no effect on short-term memory.

      Expression of Inx5JF02877 under the control of Scer\GAL4ey-OK107, Scer\GAL4VT049246, or Scer\GAL4c739 does not cause any obvious difference in the gross morphology of the mushroom body, compared to controls.

      (Shyu et al., 2019)

      Expression of Inx5JF02877 under the control of Scer\GAL417d, or the split-GAL4 pair of Scer\GAL4DBD.R14C08 and Hsap\RELAAD.R12C11, significantly impairs visual short term memory following training with pain stimulus in adult flies, compared to controls.

      (Liu et al., 2016)

      Expression of Inx5JF02877 under the control of Scer\GAL4tj.PU (along with expression of UAS-Dcr2 to increase RNAi efficiency) does not cause sterility.

      (Smendziuk et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Inx5JF02877
      inx5JF02877
      (Smendziuk et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)