FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\miple1JF02904
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General Information
Symbol
Dmel\miple1JF02904
Species
D. melanogaster
Name
FlyBase ID
FBal0240871
Feature type
allele
Associated gene
Dmel\miple1
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02904}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF02904}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02904
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Knockdown of miple1, through expression of miple1JF02904 under the control of Scer\GAL4hs.2sev or Scer\GAL4GMR.PU induces an ommatidial rotation phenotype.

      (Muñoz-Soriano et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Knockdown of miple1, through expression of miple1JF02904 under the control of Scer\GAL4hs.2sev enhances the nmoScer\UAS.cUa-induced eye phenotype.

      (Muñoz-Soriano et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      miple1JF02904/Scer\GAL4GMR.PU rescues miple1UAS.Tag:HA

      (Muñoz-Soriano et al., 2013)
      Comments

      Expression of miple1Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PU results in a clear rough eye phenotype, in which tangential sections display rotation defects but mainly defects in photoreceptor recruitment. This phenotype is dosage-sensitive, as it is markedly suppressed by reducing miple1 expression through expression of miple1JF02904.

      (Muñoz-Soriano et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      miple1JF02904
      mipleJF02904
      Name Synonyms
      Secondary FlyBase IDs
        References (2)