FlyBase Allele Report: Dmel\Spn88Ea[UAS.cAa]

General Information

Symbol

Dmel\Spn88Ea^UAS.cAa

Species

D. melanogaster

Name

FlyBase ID

FBal0241175

Feature type

allele

Associated gene

Dmel\Spn88Ea

Associated Insertion(s)

Carried in Construct

P{UAS-Spn88Ea.A}

Also Known As

UAS-spn5

Key Links

Transgenic product class

wild_type

(Ahmad et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ahmad et al., 2009)

Mutagen

in vitro construct

(Ahmad et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-Spn88Ea.A}

Cytology

Description

UASt regulatory sequences drive expression of Spn88Ea coding sequences.

(Ahmad et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Spn88Ea

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Overexpression of Spn5^Scer\UAS.cAa in the eye under the control of Scer\GAL4^GMR.PF does not cause an eye phenotype.

(Ahmad et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF is a suppressor of increased cell death phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF, Spn88Ea^c01214/Spn5[+]

(Ahmad et al., 2009)

Phenotype Manifest In

Suppressor of

Statement

Reference

Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF, Spn88Ea^c01214/Spn5[+]

(Ahmad et al., 2009)

NOT Suppressor of

Statement

Reference

Spn88Ea^UAS.cAa, Scer\GAL4^GMR.PF is a non-suppressor of photoreceptor phenotype of Hsap\CHMP2B^Intron5.UAS, Scer\GAL4^GMR.PF

(Ahmad et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of Spn5^Scer\UAS.cAa in the eye under the control of Scer\GAL4^GMR.PF completely suppresses the enhancement effect of Spn5^c01214/+ on the Hsap\CHMP2B^{Intron5.Scer\UAS} locus.

Expression of Spn5^Scer\UAS.cAa in the eye under the control of Scer\GAL4^GMR.PF completely suppresses the enhancement effect of Df(3R)ED5664/+ on the Hsap\CHMP2B^{Intron5.Scer\UAS} locus.

Expression of Spn5^Scer\UAS.cAa in the eye under the control of Scer\GAL4^GMR.PF suppresses the external eye phenotype caused by Hsap\CHMP2B^{Intron5.Scer\UAS} expression. However, Spn5^Scer\UAS.cAa overexpression does not rescue the photoreceptor degeneration phenotype.

(Ahmad et al., 2009)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Spn5^Scer\UAS.cAa

Spn88Ea^Scer\UAS.cAa

Spn88Ea^UAS.cAa

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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