FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\L1camRSLE+.UAS
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General Information
Symbol
Mmus\L1camRSLE+.UAS
Species
M. musculus
Name
FlyBase ID
FBal0241456
Feature type
allele
Associated gene
Mmus\L1cam
Associated Insertion(s)
Carried in Construct
P{UAS-L1CAM.RSLE+}
Transgenic product class
wild_type
(Kristiansen et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Kristiansen et al., 2005)
Mutagen
in vitro construct
(Kristiansen et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-L1CAM.RSLE+}
Cytology
Description

UASt regulatory sequences drive expression of the non-neuronal RSLE+ isoform of Mmus\L1cam.

(Kristiansen et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\L1cam
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Mmus\L1camRSLE+.Scer\UAS under the control of Scer\GAL4MS1075 induces few phenotypic alterations. No ectopic expression alterations are found in the ocellar sensory system and only a weak gain of function phenotype is observed in the wing.

      (Kristiansen et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4MS1075/Mmus\L1camRSLE+.UAS is a suppressor of abnormal neuroanatomy phenotype of Nrgl3

      (Kristiansen et al., 2005)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4MS1075/Mmus\L1camRSLE+.UAS is a suppressor of ocellar nerve phenotype of Nrgl3

      (Kristiansen et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Mmus\L1camRSLE+.Scer\UAS under the control of Scer\GAL4MS1075 in Nrgl3 mutant individuals rescues the axonal defects in OP axons.

      (Kristiansen et al., 2005)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\L1camRSLE+.Scer\UAS
      Mmus\L1camRSLE+.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)