FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tweek+tHB69
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General Information
Symbol
Dmel\tweek+tHB69
Species
D. melanogaster
Name
FlyBase ID
FBal0241652
Feature type
allele
Associated gene
Dmel\tweek
Associated Insertion(s)
Carried in Construct
P{tweek+tHB69}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Verstreken et al., 2009)
wild_type
(Verstreken et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Verstreken et al., 2009)
wild_type
(Verstreken et al., 2009)
Mutagen
in vitro construct
(Verstreken et al., 2009)
Progenitor genotype
Carried in construct
P{tweek+tHB69}
Cytology
Description

Genomic fragment containing tweek.

(Verstreken et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
tweek
Encoded product / tool
tweek
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2L:16,877,514..16,921,102 [+]
Comment:

Genomic fragment is based on reported primer sequences and contains CG34313, CG31743, CG6115, tweek, CG42556 CG31805, CG12288, and ApepP.

(Verstreken et al., 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tweek+tHB69 rescues tweek2/tweek1

      (Khuong et al., 2010)

      tweek+tHB69 rescues tweek2/tweek1

      (Verstreken et al., 2009)

      tweek+tHB69 rescues tweek2

      (Verstreken et al., 2009)
      Comments

      Expression of the tweek+tHB69 genomic fragment rescues the neuromuscular junction overgrowth seen in tweek1/tweek2 third instar larvae.

      (Khuong et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tweek+tHB69
      Name Synonyms
      Secondary FlyBase IDs
        References (2)