DysbUAS.Venus/Scer\GAL4RapGAP1-OK6 is a non-suppressor of abnormal neurophysiology | wandering third instar larval stage | conditional phenotype of PldnΔ1
DysbUAS.Venus/Scer\GAL4RapGAP1-OK6 is a non-suppressor of synapse | wandering third instar larval stage | conditional phenotype of PldnΔ1
The expression of DysbScer\UAS.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4RapGAP1-OK6 does not suppress either the increased rate of depletion or the decreased rate of recovery of the synaptic vesicle pool upon high-frequency stimulation of the neuromuscular junction exhibited by PldnΔ1 homozygous wandering third instar larvae.
Scer\GAL4elav-C155/DysbUAS.Venus rescues Dysb[+]/Dysbe01028
DysbUAS.Venus/Scer\GAL4RapGAP1-OK6 partially rescues Dysbe01028
The expression of DysbScer\UAS.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4RapGAP1-OK6 partially suppresses both the increased rate of depletion and the decreased rate of recovery of the synaptic vesicle pool upon high-frequency stimulation of the neuromuscular junction exhibited by Dysbe01028 homozygous wandering third instar larvae.
The increased number of boutons on neuromuscular junctions observed in Dysbe01028/+ heterozygous third instar larvae is suppressed by expression of DysbScer\UAS.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4elav-C155 in the mutant background.
Expression of dysbScer\UAS.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4elav-C155 rescues homeostatic compensation after treatment of neuromuscular junctions with with philanthotoxin-433 in dysbe01028 mutants.