FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DbxUAS.fl
Open Close
General Information
Symbol
Dmel\DbxUAS.fl
Species
D. melanogaster
Name
FlyBase ID
FBal0241890
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of Dbx coding sequences.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of DbxScer\UAS.fl under the control of Scer\GAL4elav-C155 in all postmitotic neurons leads to a decrease in the ability of many neurons to extend axons. For example, 93% of hemisegments exhibit a significant decrease in motor axon projection into the periphery, with thinning or loss of the ISN nerve (within which U and RP2 motoneurons project axons), the SNc nerve (CoR motoneurons) and the SNb nerve (U and AC motoneurons). Thin and broken longitudinal connectives between neuromeres, as well as an occasional increase in the apparent size of the axonal scaffold within neuromeres, are found at 100% penetrance.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
DbxScer\UAS.fl
DbxUAS.fl
Name Synonyms
Secondary FlyBase IDs
    References (2)