FB2026_03 , released September 17, 2026
Allele: Dmel\brunAla
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General Information
Symbol
Dmel\brunAla
Species
D. melanogaster
Name
FlyBase ID
FBal0242049
Feature type
allele
Associated gene
Dmel\brun
Associated Insertion(s)
Carried in Construct
P{brun.Ala}
Key Links
Transgenic product class
missense_variant
(Robinett et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Robinett et al., 2009)
Mutagen
in vitro construct
(Robinett et al., 2009)
Progenitor genotype
P{brun.+t5.9}
(Robinett et al., 2009)
Carried in construct
P{brun.Ala}
Cytology
Description

Genomic fragment containing brun coding sequence, 5' UTR and 700bp of 5' DNA (including 500 bp of the upstream gene, CG2614, but no other known genes) from P1 clone DS02109, fused to an additional 100 bp of the 3' UTR of brun. The brun open reading frame is tagged at the C-terminal end with EGFP . Six conserved codons encoding charged residues have been mutated To Ala (amino acid replacements K244A, R249A, K252A, D256A, E276A and D283A).

(Robinett et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
brun
Encoded product / tool
brun
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      brunAla fails to rescue brunZ3358/Df(2L)pr2b

      (Robinett et al., 2009)
      Comments

      bruAla fails to rescue the male meiotic cytokinesis defects seen in bruZ3358/Df(2L)pr2b spermatocytes.

      (Robinett et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bruAla
      brunAla
      Name Synonyms
      Secondary FlyBase IDs
        References (1)