FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lgr1JF02659
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General Information
Symbol
Dmel\Lgr1JF02659
Species
D. melanogaster
Name
FlyBase ID
FBal0242248
Feature type
allele
Associated gene
Dmel\Lgr1
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02659}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF02659}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02659
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Lgr1JF02659 under the control of Scer\GAL4elav-C155 does not affect the expected increase in food consumption induced by dietary amino acids, as observed in controls.

      (Yang et al., 2018)

      Expression of Lgr1JF02659 (together with UAS-Dicer2 to enhance RNAi efficiency) under the control of Scer\GAL4αTub84B.PL does not disrupt the growth inhibition undamaged (anterior) tissues - eye discs - in third instar larvae (104 hr after egg laying, AEL) following targeted irradiation (limited to posterior tissues and administered in late second instar, at 80 hr AEL) which is observed in wild-type larvae, however the developmental delay the regenerative growth of damaged tissues produces is significantly longer than in controls.

      (Jaszczak et al., 2016)

      Expression of Lgr1JF02659 under the control of Scer\GAL4elav.PU in adult females significantly decreases locomotor activity in fed conditions, compared to controls; like controls, locomotor activity is significantly increased under starvation conditions.

      (Yu et al., 2016)

      Expression of Lgr1JF02659 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia.

      (Ugrankar et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      FshJF02659
      Lgr1JF02659
      Name Synonyms
      Secondary FlyBase IDs
        References (6)