FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hepNIG.2190R
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General Information
Symbol
Dmel\hepNIG.2190R
Species
D. melanogaster
Name
FlyBase ID
FBal0243038
Feature type
allele
Associated gene
Dmel\hep
Associated Insertion(s)
Carried in Construct
P{NIG.2190R}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Rallis et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Rallis et al., 2010)
Mutagen
in vitro construct
(Rallis et al., 2010)
Progenitor genotype
Carried in construct
P{NIG.2190R}
Cytology
Description

UASt sequences drive expression of a hep RNAi construct.

(Rallis et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-2190R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  cancer
      modeled by scribHMS01490
      (Kumar and Srikrishna, 2025)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of hepNIG.2190R in the posterior compartment of the imaginal wing disc, under the control of Scer\GAL4en.PU or Scer\GAL4hh.PU does not affect levels of cell death.

      (Wong et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      There is a significant reduction in chromosome instability tolerance induced by mad2GD16427 expression, when hepNIG.2190R is expressed in imaginal wing discs under the control of Scer\GAL4en.PU or Scer\GAL4hh.PU. This leads to an increase in cell death.

      (Wong et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hepNIG.2190R
      Name Synonyms
      Secondary FlyBase IDs
        References (5)