FlyBase Allele Report: Dmel\be[EY08069]

General Information

Symbol

Dmel\be^EY08069

Species

D. melanogaster

Name

FlyBase ID

FBal0243158

Feature type

allele

Associated gene

Dmel\be

Associated Insertion(s)

P{EPgy2}be^EY08069

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{EPgy2}be^EY08069

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:15,024,804..15,024,804 [-]

(Zhao et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory (with be^P1)

(Zhao et al., 2009)

abnormal memory | recessive

(Zhao et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

In be^EY08069 homozygotes and be^P1/be^EY08069 adults, long-term memory resulting from Pavlovian olfactory learning tested 1 day after spaced training (10 training sessions with a 15 minute rest between each) is significantly impaired. However, no effect is seen on long term memory tested 1 day after massed training (10 training sessions with no intervals) or on the rate of memory loss after after a single training session.

(Zhao et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scamp[+]/Scamp^EP1593, be^EY08069 has abnormal neurophysiology | dominant phenotype

(Zhao et al., 2009)

Scamp[+]/Scamp^EP1593, be^EY08069 has abnormal memory | dominant phenotype

(Zhao et al., 2009)

Phenotype Manifest In

Other

Statement

Reference

Scamp[+]/Scamp^EP1593, be^EY08069 has embryonic/larval neuromuscular junction phenotype

(Zhao et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

In be^EY08069/+; Scamp^EP1593/+ adults, long-term memory resulting from Pavlovian olfactory learning tested 1 day after spaced training (10 training sessions with a 15 minute rest between each) is significantly impaired. This effect is not seen in either heterozygote alone. No effect is seen on long term memory tested 1 day after massed training (10 training sessions with no intervals).

In be^EY08069/+; Scamp^EP1593/+ larvae, the mean amplitudes of evoked excitatory junction potentials at neuromuscular junctions are significantly lower than that seen in wild-type or either heterozygote alone.

(Zhao et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

16003

y¹ w^67c23 P{EPgy2}be^EY08069 hiw^EY08069

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

be^EY08069

ben^EY08069

(Zhao et al., 2009)

ben^EY

(Zhao et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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