FB2026_02 , released June 18, 2026
Allele: Dmel\Dap160UAS.cTa
Open Close
General Information
Symbol
Dmel\Dap160UAS.cTa
Species
D. melanogaster
Name
FlyBase ID
FBal0243188
Feature type
allele
Associated gene
Dmel\Dap160
Associated Insertion(s)
Carried in Construct
P{UAS-Dap160.T}
Key Links
Transgenic product class
wild_type
(Tang et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tang et al., 2005)
Mutagen
in vitro construct
(Tang et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Dap160.T}
Cytology
Description

UAS regulatory sequences drive expression of Dap160 coding sequences.

(Tang et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Dap160
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      High levels of Dap160Scer\UAS.cTa overexpression in SOP cells and their descendants, under the control of Scer\GAL4sca-537.4 leads to more-numerous external sensory organs in a dosage-dependent manner. In addition, large balding patches are also observed. Clusters of neurons are observed underneath the balding patches, unlike in wild-type, where only a single neuron is found.

      (Tang et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of one copy each of Eps-15Scer\UAS.cTa and Dap160Scer\UAS.cTa in SOP cells and their descendants, under the control of Scer\GAL4sca-537.4 results in clusters of hairs and areas of balding, as well as more-numerous neurons underneath the balding patches in an additive phenotype.

      (Tang et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dap160Scer\UAS.cTa
      Dap160UAS.cTa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)